Casemiro appeared to have equalized for United with a header just under ten minutes before the end, leveling the score after Crysencio Summerville’s opener in the 74th minute.
However, United’s hopes were dashed when referee David Coote was summoned by the Video Assistant Referee to review Matthijs de Ligt’s tackle on Danny Ings in the penalty area with three minutes remaining.
Despite protests from United players regarding a potential handball by Ings, Coote awarded the penalty, which Bowen calmly converted, sending it past Andre Onana.
United dominated possession and created chances in the first half at the London Stadium but struggled to capitalize on their opportunities.
After a lackluster first half, West Ham improved in the second half, launching several attacks on United’s goal and eventually scoring when Summerville redirected Ings’ mishit shot into the net.